The Malayalee Association of Saint Louis (STLMA) came into existence in 1991 to foster brotherhood and ties between all malayalees in the city of Saint Louis. The association seeks to preserve the North American Malayalee integrity and promotes Kerala cultural identity. Saint Louis Malayalee Association is comprised of over 300 Malayalee families.

The first recorded arrival of an Indian visitor to America (Salem, Massacchusetts) was on December 29 1790. Ever since, people from India have settled in the United States. The immigration Act of 1960 gave an impetus to this. According to the latest census, there are 1.3 million Indian Americans in the U.S of which around 500,000 are Keralites.Most of the Malayalees who arrived in Saint Louis area in the later part of the last century were employees in the medical profession or students who studied at Washu, SLU, UMSL or UMC. With the IT boom Saint Louis witnessed a steady inflow of Malayalee IT professionals.